The 21^st International Conference on Mechatronics – Mechatronika 2024 will be held during December 4 – 6, 2024, in Brno, Czech Republic. The program will consist of contributed papers, there will be no more than two parallel sessions, depending upon topic grouping. Themes will be drawn from, but not limited to the following: Modeling and Simulation, Robotics, Actuators and Control, Power Electronics, Information and Communication Technologies, Industrial Applications, Energy Harvesting, Sensors, Measurement and Diagnostics, Military Technologies, Biomechatronics, Industry 4.0, Education.